Category: Nutritional

Other Names: DIM

Where I3C, as it is frequently called, has been tested and documented in humans results are highly promising. Indole-3-carbinol reduced or halted the formation of precancerous lesions (papillomas) in 12 out of 18 people with recurrent respiratory tract papillomas. In addition, in a small double-blind trial, supplementation with 200 or 400 mg of indole-3-carbinol per day for 12 weeks reversed early-stage cervical cancer in 8 of 17 women. Preliminary studies have also shown indole-3-carbinol has significantly increased the conversion of estrogen from cancer-producing forms to nontoxic breakdown products. Indole-3-carbinol is found in highest concentrations in broccoli, but is also found in other cruciferous vegetables, such as cauliflower, cabbage, and kale. This treatment would be indicated for those with hormonal related cancers. Note: Di-indole methane is considered a stronger metabolite of I3C.

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